Journal of clinical epidemiology, 2003-05, Vol.56 (5), p.395-407
2003
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Details
- Autor(en) / Beteiligte
- Titel
- Defining clinically meaningful change in health-related quality of life
- Ist Teil von
- Journal of clinical epidemiology, 2003-05, Vol.56 (5), p.395-407
- Ort / Verlag
- New York, NY: Elsevier Inc
- Erscheinungsjahr
- 2003
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- This article reviews current approaches to defining clinically meaningful change in health-related quality of life (HRQOL) and provides guidelines for their use. Definitions of clinically meaningful change are discussed. Two broad methods for identifying clinically meaningful change are contrasted: anchor-based methods and distribution-based methods. Anchor-based methods include cross-sectional approaches and longitudinal approaches. Distribution-based methods include those based on statistical significance, sample variability, and measurement precision. Anchor-based and distribution-based methods have advantages and limitations, and neither seems to be superior to the other. An integrated system for defining clinically meaningful change is recommended that combines anchor-based and distribution-based methods. We propose a new terminology for describing meaningful change derived from anchor-based and distribution-based methods.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0895-4356eISSN: 1878-5921DOI: 10.1016/S0895-4356(03)00044-1Titel-ID: cdi_proquest_miscellaneous_73381533
- Format
- –
- Schlagworte
- Anchor-based methods, Biological and medical sciences, Chronic illnesses, Clinically meaningful change, Computerized, statistical medical data processing and models in biomedicine, Criterion-referenced change, Disease, Distribution-based methods, Epidemiology, Health maintenance organizations, Health Status, Health-related quality of life, HMOs, Humans, Life Style, Medical sciences, Medical statistics, Methods, Minimally important difference, Mortality, Older people, Palliative care, Precision-referenced change, Prognosis, Quality of Life, Statistics as Topic, Treatment Outcome, Weight control