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Prospective study of screening for stomach cancer in Japan
International journal of cancer, 2003-08, Vol.106 (1), p.103-107
Mizoue, Tetsuya
Yoshimura, Takesumi
Tokui, Noritaka
Hoshiyama, Yoshiharu
Yatsuya, Hiroshi
Sakata, Kiyomi
Kondo, Takaaki
Kikuchi, Shogo
Toyoshima, Hideaki
Hayakawa, Norihiko
Tamakoshi, Akiko
Ohno, Yoshiyuki
Fujino, Yoshihisa
Kaneko, Satoshi
2003
Details
Autor(en) / Beteiligte
Mizoue, Tetsuya
Yoshimura, Takesumi
Tokui, Noritaka
Hoshiyama, Yoshiharu
Yatsuya, Hiroshi
Sakata, Kiyomi
Kondo, Takaaki
Kikuchi, Shogo
Toyoshima, Hideaki
Hayakawa, Norihiko
Tamakoshi, Akiko
Ohno, Yoshiyuki
Fujino, Yoshihisa
Kaneko, Satoshi
Titel
Prospective study of screening for stomach cancer in Japan
Ist Teil von
International journal of cancer, 2003-08, Vol.106 (1), p.103-107
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2003
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
Although screening for stomach cancer is a widespread community service in Japan, the benefits of the screening program remain unclear. Our study investigated prospectively the relation between participation in stomach‐cancer screening during the past 12 months and subsequent deaths. Data was derived from the Japan Collaborative Cohort Study, in which 480 stomach‐cancer deaths were identified during an 8‐year follow‐up period. Cox proportional hazard regression was used to estimate the relative risk of death from stomach cancer and that from other causes while adjusting for potential confounding factors. In men, screening participation was associated significantly with a reduced risk of death from stomach cancer (relative risk [RR] = 0.54; 95% confidence interval [CI] = 0.41–0.70). The extent of the risk reduction was greater than potential health selection (for deaths other than stomach, RR = 0.71). The adjustment for potential confounding variables, however, attenuated the difference in risk of death (stomach cancer, RR = 0.65; other causes, RR = 0.71). In women, the magnitude of the association between screening participation and death from stomach cancer (RR = 0.74; 95% CI = 0.52–1.07) was equal to that for deaths from non‐stomach cancers (RR = 0.74). Subgroup analysis showed that women with a parental history of stomach cancer had a reduced risk of death from stomach cancer associated with screening (RR = 0.32; 95% CI = 0.12–0.87). The present results underline the potential for selection bias in observational studies, and thus it remains an open question whether screening for stomach cancer is effective. © 2003 Wiley‐Liss, Inc.
Sprache
Englisch
Identifikatoren
ISSN: 0020-7136
eISSN: 1097-0215
DOI: 10.1002/ijc.11183
Titel-ID: cdi_proquest_miscellaneous_73372804
Format
–
Schlagworte
Adult
,
Age Factors
,
Aged
,
Biological and medical sciences
,
Female
,
Gastroenterology. Liver. Pancreas. Abdomen
,
Humans
,
Japan
,
Male
,
Mass Screening
,
Medical sciences
,
Middle Aged
,
Proportional Hazards Models
,
Prospective Studies
,
Risk
,
stomach neoplasms
,
Stomach Neoplasms - diagnosis
,
Stomach Neoplasms - pathology
,
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
,
Time Factors
,
Tumors
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