Details

Autor(en) / Beteiligte

• Martin, Daniel C., DDS
• O'Ryan, Felice S., DDS
• Indresano, A. Thomas, DMD
• Bogdanos, Pete
• Wang, Benjamin
• Hui, Rita L., PharmD, MS
• Lo, Joan C., MD

Titel

Characteristics of Implant Failures in Patients With a History of Oral Bisphosphonate Therapy

Ist Teil von

• Journal of oral and maxillofacial surgery, 2010-03, Vol.68 (3), p.508-514

Ort / Verlag

New York, NY: Elsevier Inc

Erscheinungsjahr

2010

Quelle

MEDLINE

Beschreibungen/Notizen

• Purpose This study examines the pattern of implant failures reported in a large cohort of patients who received oral bisphosphonate therapy. Materials and Methods A total of 8,572 individuals who received oral bisphosphonate drugs returned a dental survey that obtained information pertaining to implant placement and related complications. Among the 589 individuals reporting dental implants, 16 reported implant failures that were verified by dental records. Implant placement, timing of failure, and bisphosphonate duration were ascertained to determine the characteristics of implant loss in the setting of oral bisphosphonate exposure. Results Among the 16 patients (all women, aged 70.2 ± 7.6 yrs) there were 26 implant failures; 8 had failure of 12 implants in the maxilla and 9 had failure of 14 implants in the mandible. Early failure (≤1 yr after placement) was experienced by 8 patients (8 implants), whereas late failures (>1 yr after placement) occurred in 10 patients (18 implants); 2 patients had both early and late failures. Conclusions Overall, few patients reported implant failures. However, among these, there were more late than early failures and a slightly higher proportion of failures in the mandible versus the maxilla. Further studies should investigate the role of chronic bisphosphonate therapy in implant survival and long-term implant osseointegration.