Details

Autor(en) / Beteiligte

• Spiteri, Christian
• Moses, John E.

Titel

Copper‐Catalyzed Azide–Alkyne Cycloaddition: Regioselective Synthesis of 1,4,5‐Trisubstituted 1,2,3‐Triazoles

Ist Teil von

• Angewandte Chemie International Edition, 2010-01, Vol.49 (1), p.31-33

Ort / Verlag

Weinheim: WILEY‐VCH Verlag

Erscheinungsjahr

2010

Quelle

MEDLINE

Beschreibungen/Notizen

• Clicking along nicely: Few methods have been reported to be an efficient entry to trisubstituted triazoles with high regioselectivity. This challenge has inspired a search for new reactivity and the development of new chemical approaches. The development of an efficient, robust, one‐pot procedure as a route to highly decorated trisubstituted triazoles will be an added bonus to the range of click reactions (see scheme).