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Carotid artery stenting in octogenarians using a proximal endovascular occlusion cerebral protection device: A multicenter registry
Catheterization and cardiovascular interventions, 2010-07, Vol.76 (1), p.9-15
Micari, Antonio
Stabile, Eugenio
Cremonesi, Alberto
Vadalà, Giuseppe
Castriota, Fausto
Pernice, Vincenzo
Sorropago, Giovanni
Rubino, Paolo
Biamino, Giancarlo
2010
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Micari, Antonio
Stabile, Eugenio
Cremonesi, Alberto
Vadalà, Giuseppe
Castriota, Fausto
Pernice, Vincenzo
Sorropago, Giovanni
Rubino, Paolo
Biamino, Giancarlo
Titel
Carotid artery stenting in octogenarians using a proximal endovascular occlusion cerebral protection device: A multicenter registry
Ist Teil von
Catheterization and cardiovascular interventions, 2010-07, Vol.76 (1), p.9-15
Ort / Verlag
Hoboken: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2010
Quelle
MEDLINE
Beschreibungen/Notizen
Background: Carotid stenting (CAS) has been proposed as an alternative to carotid endoarterectomy also in elderly patients with discrepant results. However, the use of proximal neuroprotection devices have not been evaluated in octogenarians. Purpose: The aim of this multicenter prospective registry was to demonstrate that CAS in octogenarians is safe and effective if performed in high‐volume centers by experienced operators. Methods: From July 2005 to May 2009, a total of 198 octogenarians patients, in three different institutions, were included in this registry. All patients underwent CAS using proximal endovascular occlusion device (Mo.Ma. device Invatec, Roncadelle, Italy). An independent neurologist evaluated all patients. The primary endpoint was death and stroke rate at 30 days. Results: 198 octogenarians (135 men; mean age: 83.2 years) were included in the registry. 39.4% of the patients were symptomatic. Procedural success was 100%. In‐hospital complications: Two minor and two major strokes (2.02%) occurred. No device‐related complications and no serious access site complication were noted. Between discharge and 30‐day follow‐up, one patient died due to a cardiac arrest. The overall 30‐day combined stroke/death rate was 2.52%, resulting in 1.61% event incidence in asymptomatic and 3.9% in symptomatic patients (P = ns). Logistic regression did not identify independent predictor of neurological events, except in the female gender. Conclusion: This multicenter prospective registry shows that CAS performed with proximal flow blockage is safe and feasible also in octogenarians. Thirty days death/stroke rates are similar to those of the overall population and within the International guidelines. © 2010 Wiley‐Liss, Inc.
Sprache
Englisch
Identifikatoren
ISSN: 1522-1946, 1522-726X
eISSN: 1522-726X
DOI: 10.1002/ccd.22503
Titel-ID: cdi_proquest_miscellaneous_733568157
Format
–
Schlagworte
Age
,
Aged, 80 and over
,
Angioplasty - adverse effects
,
Angioplasty - instrumentation
,
Angioplasty - mortality
,
Balloon Occlusion - instrumentation
,
Cardiovascular system
,
carotid angioplasty
,
Carotid artery
,
carotid stenosis
,
Carotid Stenosis - diagnosis
,
Carotid Stenosis - mortality
,
Carotid Stenosis - therapy
,
Catheterization
,
Cerebral blood flow
,
cerebrovascular disease
,
Equipment Design
,
Female
,
Geriatrics
,
Heart
,
Humans
,
Intracranial Embolism - etiology
,
Intracranial Embolism - mortality
,
Intracranial Embolism - prevention & control
,
Ischemia
,
Italy
,
Linear Models
,
Logistic Models
,
Male
,
Neuroprotection
,
Patient Selection
,
Practice Guidelines as Topic
,
Prospective Studies
,
Registries
,
Risk Assessment
,
Severity of Illness Index
,
Stents
,
Stroke
,
Stroke - etiology
,
Stroke - prevention & control
,
Time Factors
,
Treatment Outcome
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