Details

Autor(en) / Beteiligte

• Li, Zhao-Bo
• Luo, Shu-Ping
• Guo, Yi
• Xia, Ai-Bao
• Xu, Dan-Qian

Titel

The highly enantioselective Michael addition of ketones to nitrodienes catalyzed by the efficient organocatalyst system of pyrrolidinyl-thioimidazole and chiral thioureido acid

Ist Teil von

• Organic & biomolecular chemistry, 2010-01, Vol.8 (11), p.2505-2508

Ort / Verlag

England

Erscheinungsjahr

2010

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The highly enantioselective Michael addition reaction of ketones to nitrodienes was promoted efficiently by the accessible and fine-tunable organocatalytic system of pyrrolidinyl-thioimidazole and chiral thioureido acid. The corresponding adducts were afforded in good yields with high diastereoselectivities (up to 99 : 1) and excellent enantioselectivities (up to 99% ee).