Placenta (Eastbourne), 2010-03, Vol.31, p.S87-S92
2010
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Details
- Autor(en) / Beteiligte
- Titel
- Review: Functional role of uterine natural killer (uNK) cells in human early pregnancy decidua
- Ist Teil von
- Placenta (Eastbourne), 2010-03, Vol.31, p.S87-S92
- Ort / Verlag
- Netherlands: Elsevier Ltd
- Erscheinungsjahr
- 2010
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Abstract Leukocytes comprise approximately 30–40% of decidual stromal cells in early human pregnancy. The major leukocyte component is the uterine natural killer (uNK) cells. Despite over 20 years of research the functional role of these cells in situ remains unknown although they have been proposed to play roles in immunotolerance, regulation of trophoblast invasion and remodeling of the spiral arteries. Herein we review the functional roles of this important decidual cell type.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0143-4004eISSN: 1532-3102DOI: 10.1016/j.placenta.2009.12.022Titel-ID: cdi_proquest_miscellaneous_733513106
- Format
- –
- Schlagworte
- Decidua, Decidua - immunology, Female, Human, Humans, Internal Medicine, Killer Cells, Natural - immunology, Neovascularization, Physiologic - immunology, Obstetrics and Gynecology, Pregnancy, Spiral artery remodeling, Trophoblast invasion, Trophoblasts - immunology, Uterine natural killer cells, Uterus - blood supply, Uterus - immunology