Details

Autor(en) / Beteiligte

• Hussein, Aisyah, BMedSci
• Iyengar, Ajay J., MBBS, BMedSci
• Jones, Bryn, FRACP
• Donath, Susan M., MA
• Konstantinov, Igor E., MD, PhD
• Grigg, Leeanne E., MBBS, FRACP
• Wheaton, Gavin, MBBS, FRACP, FCSANZ
• Bullock, Andrew, MBBS, FRACP
• Brizard, Christian P., MD
• d'Udekem, Yves, MD, PhD

Titel

Twenty-three years of single-stage end-to-side anastomosis repair of interrupted aortic arches

Ist Teil von

• The Journal of thoracic and cardiovascular surgery, 2010-04, Vol.139 (4), p.942-949

Ort / Verlag

United States: Mosby, Inc

Erscheinungsjahr

2010

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Objective This study defined long-term results of a policy of single-stage repair of interrupted aortic arch with end-to-side anastomosis. Methods Records of 112 consecutive patients undergoing interrupted aortic arch repair between 1985 and 2007 were reviewed. Single-stage repair was performed in 95 patients, with 90 having end-to-side repair. Results There were 11 in-hospital deaths (10%). Twelve patients needed arch reintervention during the same hospital stay: 7 for residual arch obstruction and 5 for left main bronchus obstruction. Nine patients were unavailable for follow-up. After a mean of 10 ± 7 years, 6 late deaths occurred, for 18-year survival of 92% (95% confidence interval [CI], 84%–97%). Patients with end-to-side anastomoses had better 18-year survival (97%, 95% CI, 87%–99%, vs 74%, 95% CI, 44%–89%, P < .01). After discharge, 19 patients underwent further aortic arch intervention. The only factors predictive of late arch reintervention were technique other than end-to-side ( P < .001) and reoperation for left outflow tract obstruction. Freedom from arch reintervention after end-to-side repair was 78% at 18 years (95% CI, 59%–89%). Another 16 patients had significant residual obstruction. The 18-year freedom from hypertension was 88% (95% CI, 72%–95%). Conclusions Single-stage repair with end-to-side anastomosis seems the best approach for most neonates with interrupted aortic arch, because it provides relief of the arch obstruction with low early mortality. After 2 decades of experience with this approach, incidence of late hypertension seems minimal. The need for further arch reintervention warrants close follow-up of these patients.