Details

Autor(en) / Beteiligte

• Lien, Hen-Hui
• Huang, Chi-Cheng
• Wang, Pa-Chun
• Huang, Ching-Shui
• Chen, Ya-Hui
• Lin, Tzung-Li
• Tsai, Meng-Chao

Titel

Quality-of-life measures in Taiwanese adults with symptomatic gallstone disease

Ist Teil von

• Quality of life research, 2010-08, Vol.19 (6), p.769-773

Ort / Verlag

Dordrecht: Springer

Erscheinungsjahr

2010

Link zum Volltext

Quelle

EBSCOhost Psychology and Behavioral Sciences Collection

Beschreibungen/Notizen

• Purpose The objective of this study was to investigate the association of quality-of-life status with baseline laboratory findings among Taiwanese adults having symptomatic gallstone disease. Methods A prospective quality-of-life survey was administered at a tertiary referral medical center among 102 consecutive adults with symptomatic gallstone disease. Patients underwent regular laboratory testing at admission and were evaluated using the 36-Item Short-Form Health Survey (SF-36) and the Gastrointestinal Quality of Life Index (GIQLI). Correlation and regression models were used to investigate quality-of-life predictors. Results Compared with the general Taiwanese adult population, patients having symptomatic gallstone disease had significantly poorer performance on all eight SF-36 subscales (P < 0.001). Total GIQLI showed moderate to strong correlation with all eight SF-36 subscale scores (y = 0.29 ~ 0.62, P <0.05). In multivariate analysis, serum levels of direct bilirubin (β = -32.6, P = 0.001) and alkaline phosphatase (β = -13.6, P = 0.032) were predictive of worse total GIQLI (adjusted R² = 0.183). Conclusions Symptomatic gallstone disease may considerably affect patient quality of life in terms of general health status and gastrointestinal-specific measures. Before gallstone surgery, serum levels of direct bilirubin and alkaline phosphatase significantly correlated with qualityof-life measures and can be used to evaluate patient wellbeing at admission.