Angewandte Chemie (International ed.), 2010-03, Vol.49 (11), p.1967-1970
2010
Details
- Autor(en) / Beteiligte
- Titel
- Efficient Protocol for NMR-Spectroscopy-Based Structure Determination of Protein Complexes in Solution
- Ist Teil von
- Angewandte Chemie (International ed.), 2010-03, Vol.49 (11), p.1967-1970
- Ort / Verlag
- Weinheim: Wiley-VCH Verlag
- Erscheinungsjahr
- 2010
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Putting the pieces together: An efficient, generally applicable approach for structural analysis of protein complexes and multidomain proteins in solution based on NMR spectroscopy is presented. Starting from available high‐resolution structures of individual domains or subunits, the overall domain arrangement is calculated from NMR spectroscopy data that can be obtained for high‐molecular‐weight complexes.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1433-7851eISSN: 1521-3773DOI: 10.1002/anie.200906147Titel-ID: cdi_proquest_miscellaneous_733439305
- Format
- –
- Schlagworte
- Humans, Magnetic Resonance Spectroscopy, NMR spectroscopy, Nuclear Proteins - chemistry, paramagnetic relaxation enhancement, Protein Structure, Tertiary, protein structures, residual dipolar coupling, Ribonucleoproteins - chemistry, RNA - chemistry, Solutions - chemistry, Splicing Factor U2AF, structural biology