Clinical infectious diseases, 2010-07, Vol.51 (2), p.185-188
2010
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Details
- Autor(en) / Beteiligte
- Titel
- Palivizumab-Resistant Human Respiratory Syncytial Virus Infection in Infancy
- Ist Teil von
- Clinical infectious diseases, 2010-07, Vol.51 (2), p.185-188
- Ort / Verlag
- Oxford: The University of Chicago Press
- Erscheinungsjahr
- 2010
- Quelle
- Oxford Journals 2020 Medicine
- Beschreibungen/Notizen
- Palivizumab-resistant respiratory syncytial virus was isolated from an infant treated with palivizumab. A stable mutation at codon 276 led to a nearly complete resistance to palivizumab. Additional studies revealed a second mutation at codon 272. Further passage of the virus led to a complete loss of binding of palivizumab.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1058-4838eISSN: 1537-6591DOI: 10.1086/653534Titel-ID: cdi_proquest_miscellaneous_733331523
- Format
- –
- Schlagworte
- Amino Acid Substitution - genetics, Amino acids, Antibodies, Antibodies, Monoclonal - pharmacology, Antibodies, Monoclonal, Humanized, Antiviral Agents - pharmacology, Babies, Biological and medical sciences, BRIEF REPORTS, Cell culture techniques, DNA Mutational Analysis, Dosage, Drug resistance, Drug Resistance, Viral, Human respiratory syncytial virus, Human viral diseases, Humans, Immunomodulators, Infant, Infant, Newborn, Infections, Infectious diseases, Male, Medical sciences, Mutation, Mutation, Missense, Palivizumab, Pharmacology. Drug treatments, Rats, Respiratory Syncytial Virus Infections - virology, Respiratory Syncytial Virus, Human - drug effects, Respiratory Syncytial Virus, Human - isolation & purification, Respiratory syncytial viruses, Viral diseases, Viral diseases of the respiratory system and ent viral diseases, Virology, Viruses