Details

Autor(en) / Beteiligte

• Walther, Thomas
• Schuler, Gerhard
• Borger, Michael A.
• Kempfert, Jörg
• Seeburger, Jörg
• Rückert, Yvonne
• Ender, Jörg
• Linke, Axel
• Scholz, Markus
• Falk, Volkmar
• Mohr, Friedrich W.

Titel

Transapical aortic valve implantation in 100 consecutive patients: comparison to propensity-matched conventional aortic valve replacement

Ist Teil von

• European heart journal, 2010-06, Vol.31 (11), p.1398-1403

Ort / Verlag

Oxford: Oxford University Press

Erscheinungsjahr

2010

Link zum Volltext

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• Aims To evaluate the outcome of transapical aortic valve implantation (TA-AVI) in comparison to conventional surgery. Methods and results One hundred consecutive high-risk patients with symptomatic aortic valve stenosis received TA-AVI using the Edwards SAPIEN™ pericardial xenograft between February 2006 and January 2008. Patient age was 82.7 ± 5 years, 77 were females, logistic EuroSCORE predicted risk of mortality was 29.4 ± 13% and Society Thoracic Surgeons score risk for mortality was 15.2 ± 8.3%. Propensity score analysis was used to identify a control group of patients that underwent conventional aortic valve replacement (C-AVR). Transapical aortic valve implantation was performed successfully in 97 patients, whereas three patients required early conversion. There were no new onset neurological events in the TA-AVI group and early extubation was performed in 82 patients. Echocardiography revealed good valve function with low transvalvular gradients in all patients. Thirty-day survival was 90 ± 3 vs. 85 ± 4% for TA-AVI vs. C-AVR, and 1-year survival was 73 ± 4 vs. 69 ± 5% (P = 0.55). Conclusion Transapical aortic valve implantation is a safe, minimally invasive, and off-pump technique to treat high-risk patients with aortic stenosis. Results of the initial 100 patients are good and compare favourably to conventional surgery.