Details

Autor(en) / Beteiligte

• Pumpradit, Wadchara
• Ananworanich, Jintanat
• Lolak, Sermsak
• Shikuma, Cecilia
• Paul, Robert
• Siangphoe, Umaporn
• Chaoniti, Nithima
• Kaew-on, Peeraporn
• Paris, Robert
• Ruxrungtham, Kiat
• Valcour, Victor

Titel

Neurocognitive impairment and psychiatric comorbidity in well-controlled human immunodeficiency virus-infected Thais from the 2NN Cohort Study

Ist Teil von

• Journal of neurovirology, 2010-02, Vol.16 (1), p.76-82

Ort / Verlag

New York: Informa UK Ltd

Erscheinungsjahr

2010

Link zum Volltext

Quelle

SpringerLink (Online service)

Beschreibungen/Notizen

• This research is a cross-sectional study to determine the frequency of neurocognitive impairment and psychiatric comorbidity among Thais maintained on highly active antiretroviral therapy (HAART) with undetectable plasma human immunodeficiency virus (HIV) RNA in the 2NN Cohort. Sixty-four subjects were evaluated with neurological examinations, neuropsychological testing, and psychiatric questionnaires. Twenty-four subjects (37.5%) were found to have neurocognitive impairment, with 13 (20.3%), 10 (15.6%), and 1 (1.6%) classified as asymptomatic neurocognitive disorder (ANI), mild neurocognitive disorder (MND), and HIV-associated dementia (HAD), respectively. Three subjects (4.7%) had depression and no cases had significant symptoms of anxiety. A notable proportion of well-controlled individuals exhibited neurocognitive impairment. Anxiety and depression were uncommon.