Details

Autor(en) / Beteiligte

• Greenhalgh, Roger M
• Brown, Louise C
• Powell, Janet T
• Thompson, Simon G
• Epstein, David

Titel

Endovascular Repair of Aortic Aneurysm in Patients Physically Ineligible for Open Repair

Ist Teil von

• The New England journal of medicine, 2010-05, Vol.362 (20), p.1872-1880

Ort / Verlag

Waltham, MA: Massachusetts Medical Society

Erscheinungsjahr

2010

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Patients with large abdominal aortic aneurysms who were physically ineligible for open surgical repair were assigned to undergo endovascular repair or to receive no intervention. At a median of 3 years, aneurysm-related mortality was significantly lower with endovascular repair, but there was no difference in total mortality. Patients with large abdominal aortic aneurysms who were physically ineligible for open surgical repair were assigned to undergo endovascular repair or to receive no intervention. At a median of 3 years, aneurysm-related mortality was significantly lower with endovascular repair, but there was no difference in total mortality. Endovascular repair of abdominal aortic aneurysm was originally developed for patients who were considered to be physically ineligible for open surgical repair, 1 since it was thought that life expectancy would be prolonged by eliminating the risk of fatal rupture of an aneurysm. We designed the United Kingdom Endovascular Aneurysm Repair 2 (EVAR 2) trial to test this hypothesis. 2 The midterm results of the trial, reported in 2005, showed no benefit of endovascular repair on total or aneurysm-related mortality in up to 4 years of follow-up. 3 One factor underlying this unexpected result was an operative mortality rate that was higher than . . .