Details

Autor(en) / Beteiligte

• Lipshultz, Steven E
• Sleeper, Lynn A
• Towbin, Jeffrey A
• Lowe, April M
• Orav, E. John
• Cox, Gerald F
• Lurie, Paul R
• McCoy, Kristina L
• McDonald, Melissa A
• Messere, Jane E
• Colan, Steven D

Titel

The Incidence of Pediatric Cardiomyopathy in Two Regions of the United States

Ist Teil von

• The New England journal of medicine, 2003-04, Vol.348 (17), p.1647-1655

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2003

Quelle

MEDLINE

Beschreibungen/Notizen

• Cardiomyopathy in children is a serious disorder that often results in cardiac transplantation or death. This study was based on a 1996–1999 registry of cases in New England and in Texas, Oklahoma, and Arkansas. The overall annual incidence was 1.13 cases per 100,000 children, but the incidence was much higher among infants than in other age groups. Dilated and hypertrophic cardiomyopathies predominated. The incidence was higher in boys than in girls and in blacks than in whites. Cardiomyopathy is a very serious disorder in children, and nearly 40 percent of children who present with symptomatic cardiomyopathy receive a heart transplant or die within the first two years. 1 The time to transplantation or death for children with cardiomyopathy has not improved during the past 35 years, and the outcomes in the most economically advanced nations are no better than those in developing nations. 2 – 4 The cardiomyopathies have an associated cost of nearly $200 million per year in adults and children in the United States alone. 5 , 6 The percentage of children with cardiomyopathy who receive a heart transplant has . . .