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Attributable and absolute risk of lung cancer death by smoking status: Findings from the Japan collaborative cohort study
International journal of cancer, 2003-06, Vol.105 (2), p.249-254
Ando, Masahiko
Wakai, Kenji
Seki, Nao
Tamakoshi, Akiko
Suzuki, Koji
Ito, Yoshinori
Nishino, Yoshikazu
Kondo, Takaaki
Watanabe, Yoshiyuki
Ozasa, Kotaro
Ohno, Yoshiyuki
2003
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Ando, Masahiko
Wakai, Kenji
Seki, Nao
Tamakoshi, Akiko
Suzuki, Koji
Ito, Yoshinori
Nishino, Yoshikazu
Kondo, Takaaki
Watanabe, Yoshiyuki
Ozasa, Kotaro
Ohno, Yoshiyuki
Titel
Attributable and absolute risk of lung cancer death by smoking status: Findings from the Japan collaborative cohort study
Ist Teil von
International journal of cancer, 2003-06, Vol.105 (2), p.249-254
Ort / Verlag
New York: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2003
Quelle
Wiley Online Library - AutoHoldings Journals
Beschreibungen/Notizen
Estimating the proportion of lung cancer deaths that can be avoided is important in assessing the potential impact of antismoking efforts on the reduction of lung cancer deaths. We calculated the population attributable risk (PAR) and absolute risk of lung cancer death according to smoking status based on the Japan Collaborative Cohort (JACC) Study. The analytic cohort included 45,010 males and 55,724 females aged 40–79 years. Cox proportional hazards model was used to determine age‐adjusted relative risks and PAR according to smoking status. We also computed lung cancer mortality according to age and smoking status. In males, 52.2% and 14.8% of lung cancer deaths were attributable to current and former cigarette smoking, respectively. In females, the corresponding figures were 11.8% and 2.8%. Among current male smokers, the relative risk was strongly correlated with the intensity and duration of cigarette smoking. In contrast, the PAR was associated with an intermediate level of smoking except for the years of smoking: the largest PARs were observed in those with 20–29 cigarettes per day, 40–59 pack‐years and 20–22 years old at starting smoking. Absolute risks were estimated to increase with age and duration of smoking and not to decrease even after cessation. These findings suggest that avoidable lung cancer deaths are primarily among light to moderate smokers who are considered amenable to population‐based antismoking strategies. For all current smokers, immediate cessation is encouraged because it offers the only realistic way to avoid a substantial increase in lung cancer mortality brought about by further continuation of smoking. © 2003 Wiley‐Liss, Inc.
Sprache
Englisch
Identifikatoren
ISSN: 0020-7136
eISSN: 1097-0215
DOI: 10.1002/ijc.11043
Titel-ID: cdi_proquest_miscellaneous_73149369
Format
–
Schlagworte
Adult
,
Age Distribution
,
Aged
,
Biological and medical sciences
,
cigarette smoking
,
Cohort Studies
,
cohort study
,
Female
,
Follow-Up Studies
,
Humans
,
Japan - epidemiology
,
lung cancer
,
Lung Neoplasms - etiology
,
Lung Neoplasms - mortality
,
Male
,
Medical sciences
,
Middle Aged
,
mortality
,
Pneumology
,
population attributable risk
,
Prospective Studies
,
Risk Factors
,
Smoking - adverse effects
,
Smoking - mortality
,
Smoking Cessation - statistics & numerical data
,
Tumors of the respiratory system and mediastinum
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