UNIVERSI
TÄ
TS-
BIBLIOTHEK
P
ADERBORN
Anmelden
Menü
Menü
Start
Hilfe
Blog
Weitere Dienste
Neuerwerbungslisten
Fachsystematik Bücher
Erwerbungsvorschlag
Bestellung aus dem Magazin
Fernleihe
Einstellungen
Sprache
Deutsch
Deutsch
Englisch
Farbschema
Hell
Dunkel
Automatisch
Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist
gegebenenfalls
nur via VPN oder Shibboleth (DFN-AAI) möglich.
mehr Informationen...
Universitätsbibliothek
Katalog
Suche
Details
Zur Ergebnisliste
Ergebnis 13 von 65
Datensatz exportieren als...
BibTeX
Fibroblast growth on surface-modified dental implants: An in vitro study
Journal of biomedical materials research, 2003-03, Vol.64A (4), p.591-599
Groessner-Schreiber, Birte
Neubert, Anja
Müller, Wolf-Dieter
Hopp, Michael
Griepentrog, Michael
Lange, Klaus-Peter
2003
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Groessner-Schreiber, Birte
Neubert, Anja
Müller, Wolf-Dieter
Hopp, Michael
Griepentrog, Michael
Lange, Klaus-Peter
Titel
Fibroblast growth on surface-modified dental implants: An in vitro study
Ist Teil von
Journal of biomedical materials research, 2003-03, Vol.64A (4), p.591-599
Ort / Verlag
New York: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2003
Quelle
Wiley Online Library - AutoHoldings Journals
Beschreibungen/Notizen
A major consideration in designing dental implants is the creation of a surface that provides strong attachment between the implant and bone, connective tissue, or epithelium. In addition, it is important to inhibit the adherence of oral bacteria on titanium surfaces exposed to the oral cavity to maintain plaque‐free implants. Previous in vitro studies have shown that titanium implant surfaces coated with titanium nitride (TiN) reduced bacterial colonization compared to other clinically used implant surfaces. The aim of the present study was to examine the support of fibroblast growth by a TiN surface that has antimicrobial characteristics. Mouse fibroblasts were cultured on smooth titanium discs that were either magnetron‐sputtered with a thin layer of titanium nitride, thermal oxidized, or modified with laser radiation (using a Nd‐YAG laser). The resulting surface topography was examined by scanning electron microscopy (SEM), and surface roughness was estimated using a two‐dimensional contact stylus profilometer. A protein assay (BCA assay) and a colorimetric assay to examine fibroblast metabolism (MTT) were used. Cellular morphology and cell spreading were analyzed using SEM and fluorescence microscopy. Fibroblasts on oxidized titanium surfaces showed a more spherical shape, whereas cells on laser‐treated titanium and on TiN appeared intimately adherent to the surface. The MTT activity and total protein were significantly increased in fibroblasts cultured on titanium surfaces coated with TiN compared to all other surface modifications tested. This study suggests that a titanium nitride coating might be suitable to support tissue growth on implant surfaces. © 2003 Wiley Periodicals, Inc. J Biomed Mater Res 64A: 591–599, 2003
Sprache
Englisch
Identifikatoren
ISSN: 1549-3296, 0021-9304
eISSN: 1552-4965, 1097-4636
DOI: 10.1002/jbm.a.10417
Titel-ID: cdi_proquest_miscellaneous_73046512
Format
–
Schlagworte
3T3 Cells
,
Animals
,
Biological and medical sciences
,
Cell Culture Techniques
,
Cell Size
,
Dental Alloys - chemistry
,
Dental Alloys - metabolism
,
Dental Implants
,
fibroblasts
,
Fibroblasts - cytology
,
Fibroblasts - metabolism
,
hard coatings
,
Medical sciences
,
Mice
,
Proteins - analysis
,
Surface Properties
,
thermal oxidation
,
Titanium - chemistry
,
Titanium - metabolism
,
titanium implants
,
wettability
Weiterführende Literatur
Empfehlungen zum selben Thema automatisch vorgeschlagen von
bX