Details

Autor(en) / Beteiligte

• Asli, Bouchra
• Wechsler, Bertrand
• Lemaître, Claire

Titel

Inhibition of Tumor Necrosis Factor α and Ankylosing Spondylitis

Ist Teil von

• The New England journal of medicine, 2003-01, Vol.348 (4), p.359-361

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2003

Quelle

MEDLINE

Beschreibungen/Notizen

• To the Editor: In a recent multicenter trial, Gorman et al. (May 2 issue) 1 found that 80 percent of patients with active ankylosing spondylitis had a favorable response to etanercept. Equivalent results are obtained with infliximab. 2 Data on uveitis are still lacking. We report a case of severe uveitis in a 45-year-old man that improved with infliximab. In 1986, the patient was given a diagnosis of HLA-B27–positive ankylosing spondylitis. Since 1993, he had had recurrent bilateral anterior uveitis, leading to functional blindness of the right eye despite the use of antiinflammatory drugs, including corticosteroids. When he was seen in May . . .