Details

Autor(en) / Beteiligte

• Matteucci, Mizio
• Bhalay, Gurdip
• Bradley, Mark

Titel

Mild and Highly Chemoselective Oxidation of Thioethers Mediated by Sc(OTf)3

Ist Teil von

• Organic letters, 2003-02, Vol.5 (3), p.235-237

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2003

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Catalytic Sc(OTf)3 greatly increases the efficiency of hydrogen peroxide mediated monooxidation of alkyl−aryl sulfides and methyl cysteine containing peptides. The method is high yielding, compatible with many widely used protecting groups, suitable for solid-phase applications and proceeds with minimum over-oxidation.