Neurosurgical focus, 2002-12, Vol.13 (6), p.e2-6
2002
Details
- Autor(en) / Beteiligte
- Titel
- Bone morphogenetic proteins: basic concepts
- Ist Teil von
- Neurosurgical focus, 2002-12, Vol.13 (6), p.e2-6
- Ort / Verlag
- United States
- Erscheinungsjahr
- 2002
- Link zum Volltext
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- The cellular and molecular events governing bone formation in the embryo, healing of a fractured bone, and induced bone fusion follow a similar pattern. Discovery, purification, and recombinant synthesis of bone morphogenetic proteins (BMPs) constitute a major milestone in the understanding of bone physiology. In this review the author discusses the mechanism of action, clinical applications, dosage, and optimum carriers for BMPs. The roles played by other growth factors are also discussed.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1092-0684eISSN: 1092-0684DOI: 10.3171/foc.2002.13.6.3Titel-ID: cdi_proquest_miscellaneous_72929315
- Format
- –
- Schlagworte
- Animals, Bone Morphogenetic Proteins - administration & dosage, Bone Morphogenetic Proteins - classification, Bone Morphogenetic Proteins - physiology, Fractures, Bone - drug therapy, Fractures, Bone - metabolism, Humans, Signal Transduction - drug effects, Signal Transduction - physiology