Details

Autor(en) / Beteiligte

• Paramonov, B A
• Churilova, I V
• Zinov'ev, E V
• Chebotarev, V Yu

Titel

Erysod, erythrocyte superoxide dismutase preparation: effects on LPO processes and morphological changes in the viscera of rats with burns under conditions of delayed antishock infusion therapy

Ist Teil von

• Bulletin of experimental biology and medicine, 2002-12, Vol.134 (6), p.578-582

Ort / Verlag

United States: Springer Nature B.V

Erscheinungsjahr

2002

Quelle

SpringerLINK Contemporary (Konsortium Baden-Württemberg)

Beschreibungen/Notizen

• Biochemical and morphological changes in the kidneys, liver, heart, and lungs were studied in rats with deep burns of 20% body surface. Erysod (0.47 mg/kg/day) added to antishock therapy notably reduced the intensity of LPO processes in tissues both in cases when infusion therapy was started immediately (by 8-20% 12 h and by 5-24% 24 h after the injury) and when this therapy was 6 h delayed (by up about 36% after 12 h). This prevented injuries to visceral organs during the acute period of thermal injury and prevented the development of burn disease.