Details

Autor(en) / Beteiligte

• Wall, P. D.
• Pressman, E. K.
• Woods, J. R.

Titel

Preterm premature rupture of the membranes and antioxidants: the free radical connection

Ist Teil von

• Journal of perinatal medicine, 2002-01, Vol.30 (6), p.447-457

Ort / Verlag

Berlin: Walter de Gruyter

Erscheinungsjahr

2002

Quelle

MEDLINE

Beschreibungen/Notizen

• Aim: To discuss the role of oxidant stress in preterm, premature rupture of the membranes (PPROM). Results: There is evidence to suggest that preterm, premature rupture of the membranes occurs secondary to focal collagen damage in the fetal membranes. Conclusion: Oxidant stress caused by increased ROS formation and/or antioxidant depletion may disrupt collagen and cause premature membrane rupture. We propose that supplementation with vitamins C and E may synergistically protect the fetal membranes, and decrease the risks of PPROM.