Details

Autor(en) / Beteiligte

• Menges, Frederik
• Neuburger, Markus
• Pfaltz, Andreas

Titel

Synthesis and Application of Chiral Phosphino-Imidazoline Ligands:  Ir-Catalyzed Enantioselective Hydrogenation

Ist Teil von

• Organic letters, 2002-12, Vol.4 (26), p.4713-4716

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2002

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A series of chiral phosphino-imidazolines (PHIM ligands) 1a−j with different substituents at the stereogenic center, the nitrogen atom of the imidazoline ring, and at the phosphorus atom were synthesized. Iridium complexes derived from these ligands have been evaluated as catalysts for the enantioselective hydrogenation of unfunctionalized olefins. In several cases, higher enantiomeric excesses were observed than with analogous phosphino-oxazoline ligands.