Details

Autor(en) / Beteiligte

• Moore, Brian A.
• Duncan, Irenee M.
• Burkey, Brian B.
• Day, Terry

Titel

Incidental Metastatic Papillary Thyroid Carcinoma in Microvascular Reconstruction

Ist Teil von

• The Laryngoscope, 2002-12, Vol.112 (12), p.2170-2177

Ort / Verlag

Hoboken, NJ: John Wiley & Sons, Inc

Erscheinungsjahr

2002

Quelle

Access via Wiley Online Library

Beschreibungen/Notizen

• Objectives/Hypothesis Occult papillary thyroid carcinoma has a reported prevalence of 1% to 35% based on autopsy studies. Cervical lymphatic metastases from papillary thyroid carcinoma have been associated with a higher likelihood of recurrence with a questionable impact on survival. Without clinically evident disease in the thyroid or cervical nodes, management of these patients presents a treatment dilemma. We propose an individualized treatment plan for patients in whom metastatic papillary thyroid carcinoma is incidentally detected during neck exploration for other purposes. Study Design Retrospective review and discussion of the literature. Methods The clinical course of two patients with incidentally discovered metastatic papillary thyroid carcinoma to the cervical lymph nodes is described. Both patients had previously received head and neck irradiation in childhood and required free flap reconstruction of extensive skull base defects following extirpation of meningiomas. Results Neck dissection specimens from levels I and II obtained during exposure of recipient vessels for microvascular tissue transfer revealed papillary thyroid carcinoma in both cases. The patients subsequently underwent total thyroidectomy, neck dissection, and postoperative radioactive iodine ablation of residual thyroid tissue. After 1 year of follow‐up, both patients were without evidence of recurrent disease. Conclusions An individualized approach is justified to treat metastatic papillary thyroid carcinoma incidentally discovered during other procedures. The case reports underscore the importance of pathological analysis of surgical specimens obtained during head and neck reconstruction.