Details

Autor(en) / Beteiligte

• Neutra, Marian R.
• Kraehenbuhl, Jean-Pierre

Titel

Transepithelial transport and mucosal defence I: the role of M cells

Ist Teil von

• Trends in Cell Biology, 1992-05, Vol.2 (5), p.134-138

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

1992

Link zum Volltext

Quelle

Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)

Beschreibungen/Notizen

• How do cells of the immune system encounter the majority of antigens that enter the body through the gut and airways? The epithelia lining these systems contain a remarkable cell type, the M cell, that delivers antigens across the epithelium to lymphocytes and macrophages. In this article, Marian Neutra and Jean-Pierre Kraehenbuhl describe the structure of the M cell, its function in promoting the immune response and its exploitation by invading pathogens. In the next issue of Trends in Cell Biology, these authors will review the other immunological function of epithelia, secretion of polymeric IgA.