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Plastic bronchitis in children: A case series and review of the medical literature
Pediatric pulmonology, 2002-12, Vol.34 (6), p.482-487
Brogan, Thomas V.
Finn, Laura S.
Pyskaty, D. James
Redding, Gregory J.
Ricker, David
Inglis, Andrew
Gibson, Ronald L.
2002
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Brogan, Thomas V.
Finn, Laura S.
Pyskaty, D. James
Redding, Gregory J.
Ricker, David
Inglis, Andrew
Gibson, Ronald L.
Titel
Plastic bronchitis in children: A case series and review of the medical literature
Ist Teil von
Pediatric pulmonology, 2002-12, Vol.34 (6), p.482-487
Ort / Verlag
New York: Wiley Subscription Services, Inc., A Wiley Company
Erscheinungsjahr
2002
Quelle
Wiley-Blackwell Journals
Beschreibungen/Notizen
Plastic bronchitis is characterized by marked obstruction of the large airways by bronchial casts. We reviewed our experience and the literature to determine whether mortality rates are determined by underlying disease or cast type. We present 3 children with obstructive bronchial casts. One 3‐year‐old patient with Noonan's syndrome developed respiratory failure following surgery for tetralogy of Fallot requiring support with extracorporeal membrane oxygenation (ECMO) the first such case. There were 42 cases in the literature of children with plastic bronchitis. Casts may be divided into two types. Type I casts are inflammatory, consisting mainly of fibrin with cellular infiltrates, and occur in inflammatory diseases of the lung. Type II, or acellular casts, consist mainly of mucin with a few cells, and usually occur following surgery for congenital cardiac defects. Patients categorized by underlying disease included 31% with asthma or allergic disease, 40% with underlying cardiac defects, and 29% with other diseases. Mortality was 16%, but increased to 29% in patients with cardiac defects. Deaths occurred as long as 1 year after surgical repair for underlying defects. There were no deaths in patients with asthma. Life‐threatening events were statistically higher in patients with cardiac defects (41%) than in those with asthma (0%, P = 0.02). Higher mortality in patients with type II casts compared to type I casts did not reach statistical significance (28% vs. 6%; P = 0.06). In conclusion, patients presenting with plastic bronchitis are at high risk for serious complications, especially with underlying cardiac disease. Pediatr Pulmonol. 2002; 34:482–487. © 2002 Wiley‐Liss, Inc.
Sprache
Englisch
Identifikatoren
ISSN: 8755-6863
eISSN: 1099-0496
DOI: 10.1002/ppul.10179
Titel-ID: cdi_proquest_miscellaneous_72670779
Format
–
Schlagworte
asthma
,
Biological and medical sciences
,
Bronchi - pathology
,
Bronchitis - classification
,
Bronchitis - pathology
,
Child, Preschool
,
congenital cardiac defects
,
extracorporeal membrane oxygenation
,
Female
,
Heart Defects, Congenital - pathology
,
Heart Defects, Congenital - surgery
,
Humans
,
Infant
,
Male
,
Medical sciences
,
plastic bronchitis
,
Pneumology
,
Respiratory system : syndromes and miscellaneous diseases
,
tetralogy of Fallot
,
tricuspid atresia
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