Farmaco (Società chimica italiana : 1989), 2000-06, Vol.55 (6), p.484-491
2000
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Details
- Autor(en) / Beteiligte
- Titel
- Building a pharmacophore model for a novel class of antitubercular compounds
- Ist Teil von
- Farmaco (Società chimica italiana : 1989), 2000-06, Vol.55 (6), p.484-491
- Ort / Verlag
- Lausanne: Elsevier SAS
- Erscheinungsjahr
- 2000
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Starting from a set of 32 antitubercular compounds, for the first time a three-dimensional pharmacophore model has been derived through a computational approach based on catalyst software. The model proved to be able to identify compounds belonging to classes of molecules already reported as antitubercular agents.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0014-827XeISSN: 1879-0569DOI: 10.1016/S0014-827X(00)00072-0Titel-ID: cdi_proquest_miscellaneous_72545940
- Format
- –
- Schlagworte
- Antibacterial agents, Antibiotics. Antiinfectious agents. Antiparasitic agents, Antitubercular agents, Antitubercular Agents - chemistry, Antitubercular Agents - pharmacology, Biological and medical sciences, Computational Biology, Crystallography, X-Ray, Database search, Medical sciences, Models, Molecular, Molecular Conformation, Pharmacology. Drug treatments, Pharmacophore model, Structure-Activity Relationship