Planta medica, 2001-12, Vol.67 (9), p.865-867
2001
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- Autor(en) / Beteiligte
- Titel
- Cytotoxic Butanolides from the Stem Bark of Formosan Lindera communis
- Ist Teil von
- Planta medica, 2001-12, Vol.67 (9), p.865-867
- Ort / Verlag
- Stuttgart: Thieme
- Erscheinungsjahr
- 2001
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Abstract Two new butanolides, lincomolide A (1), lincomolide B (2), along with seven known compounds, isolinderanolide E, sepesteonol, β-sitosterol, β-sitosterol-β-glucoside, tetradecane, nonanoic acid and decanol, were isolated from the chloroform-soluble portion of the stem bark of LINDERA COMMUNIS. Compound 1 showed cytotoxicity against P-388, KB16 and A549, and 2 exhibited cytotoxicity against P-388 cancer cell lines. Moreover, 1 showed marginal activity against HT-29, and 2 against KB16, A549 and HT-29 cancer cell lines. The structures of these compounds were determined by spectral analyses.
- Sprache
- Deutsch; Englisch
- Identifikatoren
- ISSN: 0032-0943eISSN: 1439-0221DOI: 10.1055/s-2001-18840Titel-ID: cdi_proquest_miscellaneous_72363461
- Format
- –
- Schlagworte
- 4-Butyrolactone - analogs & derivatives, 4-Butyrolactone - chemistry, 4-Butyrolactone - isolation & purification, 4-Butyrolactone - pharmacology, Antineoplastic Agents, Phytogenic - chemistry, Antineoplastic Agents, Phytogenic - isolation & purification, Antineoplastic Agents, Phytogenic - pharmacology, Biological and medical sciences, Cell Division - drug effects, General pharmacology, HT29 Cells - drug effects, Humans, Letter, Lindera, Medical sciences, Pharmacognosy. Homeopathy. Health food, Pharmacology. Drug treatments, Plant Bark - chemistry, Tumor Cells, Cultured