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Reduced development of cerebral cortex in extremely preterm infants
Ist Teil von
The Lancet (British edition), 2000-09, Vol.356 (9236), p.1162-1163
Ort / Verlag
London: Elsevier Ltd
Erscheinungsjahr
2000
Link zum Volltext
Quelle
Psychology & Behavioral Sciences Collection
Beschreibungen/Notizen
Most growth in cortical connections and complexity occurs after 25 weeks. The cerebral cortex of extremely preterm infants when imaged at gestational age 38–42 weeks had less cortical surface area and was less complex than in normal infants born around term (p<0·0148 and p<0·0002, respectively), despite similar term-corrected cerebral tissue volumes. Since deficits acquired during critical periods of brain development may be permanent, these results suggest a neural substrate for the neurocognitive impairment that is frequent among such preterm infants.