Details

Autor(en) / Beteiligte

• Cortez, Karoll J.
• Erdman, Dean D.
• Peret, Teresa C. T.
• Gill, Vee J.
• Childs, Richard
• Barrett, A. John
• Bennett, John E.

Titel

Outbreak of Human Parainfluenza Virus 3 Infections in a Hematopoietic Stem Cell Transplant Population

Ist Teil von

• The Journal of infectious diseases, 2001-11, Vol.184 (9), p.1093-1097

Ort / Verlag

Chicago, IL: The University of Chicago Press

Erscheinungsjahr

2001

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• Clinical manifestations and epidemiological features are described for a cluster of 12 cases of human parainfluenza virus 3 (HPIV3) infection that occurred among 64 allogeneic hematopoietic stem cell transplant (SCT) recipients in an 11-week period during spring 2000. Upper respiratory symptoms predominated. Pneumonia occurred in 3 patients and was a contributing factor in the death of 1 patient. Exposure histories and molecular analysis of HPIV3 isolates suggested that both community acquired and nosocomially transmitted infections occurred during this outbreak. A chain of transmission within the outpatient clinic appeared to have occurred in 4 outpatients and to have extended to 2 hospitalized patients. Molecular epidemiology was useful in discerning routes of transmission in this outbreak