Biomaterials, 2002-12, Vol.23 (23), p.4549-4555
2002
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Details
- Autor(en) / Beteiligte
- Titel
- Easy assessment of the biocompatibility of Ni–Ti alloys by in vitro cell culture experiments on a functionally graded Ni–NiTi–Ti material
- Ist Teil von
- Biomaterials, 2002-12, Vol.23 (23), p.4549-4555
- Ort / Verlag
- Netherlands: Elsevier Ltd
- Erscheinungsjahr
- 2002
- Quelle
- Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
- Beschreibungen/Notizen
- The biocompatibility of nickel–titanium alloys was investigated by single-culture experiments on functionally graded samples with a stepwise change in composition from pure nickel to pure titanium, including an Ni–Ti shape memory alloy for a 50:50 mixture. This approach permitted a considerable decrease of experimental resources by simultaneously studying a full variation of composition. The results indicate a good biocompatibility for a nickel content up to about 50%. The cells used in the biocompatibility studies comprised osteoblast-like osteosarcoma cells (SAOS-2, MG-63), primary human osteoblasts (HOB), and murine fibroblasts (3T3).
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0142-9612eISSN: 1878-5905DOI: 10.1016/S0142-9612(02)00200-4Titel-ID: cdi_proquest_miscellaneous_72126205
- Format
- –
- Schlagworte
- 3T3 Cells, Alloys - chemistry, Alloys - pharmacology, Animals, Biocompatibility, Biocompatible Materials, Cell Line, Cells, Cultured, Cobalt - chemistry, Coculture Techniques, Humans, Metallic implants, Mice, Nickel - chemistry, Nickel - pharmacology, Nickel alloys, Ni–Ti shape memory alloys, Osteoblasts - metabolism, Time Factors, Titanium - chemistry, Titanium - pharmacology, Titanium alloys, Tumor Cells, Cultured, X-Ray Diffraction, X-Rays