Details

Autor(en) / Beteiligte

• Ribeiro, Antonio Luiz P
• dos Reis, Adelina Martha
• Barros, Marcio Vinicius L
• de Sousa, Marcos Roberto
• Rocha, Ana Luiza L
• Perez, Amanda Arantes
• Pereira, Jacqueline Braga
• Machado, Fernando Santana
• Rocha, Manoel Otávio C

Titel

Brain natriuretic peptide and left ventricular dysfunction in Chagas' disease

Ist Teil von

• The Lancet (British edition), 2002-08, Vol.360 (9331), p.461-462

Ort / Verlag

London: Elsevier Ltd

Erscheinungsjahr

2002

Link zum Volltext

Quelle

EBSCOhost Business Source Ultimate

Beschreibungen/Notizen

• Left ventricular dysfunction in Chagas' disease is common but can be difficult to detect. We investigated whether measurement of plasma brain natriuretic peptide (BNP) could identify patients with left ventricular dysfunction who need further investigation or treatment. Among patients with an abnormal electrocardiogram or chest radiograph, a BNP concentration of 60·7 pmol/L or higher has a sensitivity and positive predictive value of 80%, and specificity and negative predictive value of 97%. Measurement of plasma BNP concentration could be a useful method to screen patients with Chagas' disease.