Mechanisms of development, 2002-06, Vol.114 (1), p.133-135
2002
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- Autor(en) / Beteiligte
- Titel
- A novel zinc finger transcription factor resembles krox-20 in structure and in expression pattern in zebrafish
- Ist Teil von
- Mechanisms of development, 2002-06, Vol.114 (1), p.133-135
- Ort / Verlag
- Ireland: Elsevier Ireland Ltd
- Erscheinungsjahr
- 2002
- Quelle
- Elsevier ScienceDirect Journals
- Beschreibungen/Notizen
- Krx-20, a zinc finger protein, plays an essential role in hindbrain segmentation of vertebrates. Zebrafish gene frb35 encodes a novel zinc finger protein that shares a high homology with Krx-20. The expression domains of frb35 overlap those of krx-20. The expression of frb35 first occurs in the 3rd rhombomere primordium at the onset of segmentation, which is soon followed by expression in the 5th rhombomere. From mid-segmentation onward, the 5th rhombomere has a higher frb35 expression level than the 3rd rhombomere. Unlike krx20, frb35 expression persists in the 5th rhombomere until the end of pharyngula period.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0925-4773eISSN: 1872-6356DOI: 10.1016/S0925-4773(02)00038-2Titel-ID: cdi_proquest_miscellaneous_71991695
- Format
- –
- Schlagworte
- Amino Acid Sequence, Animals, DNA, Complementary - metabolism, DNA-Binding Proteins - biosynthesis, DNA-Binding Proteins - chemistry, Early Growth Response Protein 2, frb35, Hindbrain, krox-20, krx-20, Molecular Sequence Data, Protein Structure, Tertiary, Rhombomeres, Sequence Homology, Amino Acid, Time Factors, Transcription Factors - biosynthesis, Transcription Factors - chemistry, Transcription Factors - genetics, Zebrafish, Zebrafish Proteins - biosynthesis, Zebrafish Proteins - chemistry, Zebrafish Proteins - genetics, Zinc Fingers