Details

Autor(en) / Beteiligte

• Bates, Roderick W
• Satcharoen, Vachiraporn

Titel

Nucleophilic transition metal based cyclization of allenes

Ist Teil von

• Chemical Society reviews, 2002-01, Vol.31 (1), p.12-21

Ort / Verlag

England

Erscheinungsjahr

2002

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Allenes bearing a pro-nucleophile can be cyclized on treatment with a wide variety of transition metal catalysts and reagents: palladium, cobalt, ruthenium, silver, rhodium, lanthanides, gold. The nucleophilic groups can be nitrogen, oxygen or carbon based and can form rings of various sizes, often with good control of stereochemistry. A variety of mechanisms can be proposed for these reactions and the metal complex can be used to introduce a variety of functional groups during cyclization. Several heterocyclic natural products have been prepared using a selection of these reactions.