Details

Autor(en) / Beteiligte

• Blood, Anne J.
• Flaherty, Alice W.
• Choi, Ji-Kyung
• Hochberg, Fred H.
• Greve, Douglas N.
• Bonmassar, Giorgio
• Rosen, Bruce R.
• Jenkins, Bruce G.

Titel

Basal ganglia activity remains elevated after movement in focal hand dystonia

Ist Teil von

• Annals of neurology, 2004-05, Vol.55 (5), p.744-748

Ort / Verlag

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

Erscheinungsjahr

2004

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Although previous studies of focal hand dystonia have detected cortical sensorimotor abnormalities, little is known about the role of the basal ganglia in this disorder. We report here that when focal hand dystonic patients performed finger‐tapping tasks, functional magnetic resonance imaging showed persisting elevations of basal ganglia activity after the tasks ended. We posit that inhibitory control of the basal ganglia may be faulty in focal hand dystonia, and that the increases we observe in “resting” activity may mask basal ganglia abnormalities in standard imaging contrast analyses.