Details

Autor(en) / Beteiligte

• MATHERS, M. E.
• JOHNSON, S. J.
• WADEHRA, V.

Titel

How predictive is a cervical smear suggesting glandular neoplasia?

Ist Teil von

• Cytopathology (Oxford), 2002-04, Vol.13 (2), p.83-91

Ort / Verlag

Oxford UK: Blackwell Science Ltd

Erscheinungsjahr

2002

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• How predictive is a cervical smear suggesting glandular neoplasia The prevalence of endocervical adenocarcinoma and its precursors has increased, in part due to increased diagnostic awareness of these lesions. To date, limited information has been published regarding the predictive value of glandular abnormalities in cervical smears. This study details the histological follow up of 418 cervical smears showing glandular abnormality, reported in our department over a six year period from 1993 to 1998. Histological follow up was available for 395 of the 418 smears (94.50%). The overall positive predictive value (PPV) for this group of smears was 72.66% for either significant glandular or squamous pathology (at least low grade cervical glandular intraepithelial neoplasia or CIN2 on follow up biopsy), and 55.70% for significant glandular pathology alone. Examination of subcategories of abnormal glandular smear showed that the PPV increased with the degree of abnormality reported within the smears.