Details

Autor(en) / Beteiligte

• Veznedaroglu, Baybars
• Ercan, Eyup Sabri
• Kayahan, Bulent
• Varan, Azmi
• Bayraktar, Erhan

Titel

Reduced short-term obsessive-compulsive symptoms in schizophrenic patients treated with risperidone: a single-blind prospective study

Ist Teil von

• Human psychopharmacology, 2003-12, Vol.18 (8), p.635-640

Ort / Verlag

Chichester, UK: John Wiley & Sons, Ltd

Erscheinungsjahr

2003

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Background Risperidone is a widely used agent as first‐line treatment in schizophrenia with a favorable side‐effect profile. However, a number of case reports have suggested an increase in obsessive–compulsive symptoms in patients treated with risperidone. Objective The aim of this study was to investigate the effect of risperidone on obsessive–compulsive symptoms in the treatment of schizophrenia. Method Forty patients with DSM‐IV diagnosis of schizophrenia were included in the study. The Yale‐Brown obsessive compulsive scale was administered before, at the end of first and second months of treatment. Paired‐samples t‐test was used to compare the three assessments. Results There was not an increase, but a significant decrease, in YBOCS scores over time during risperidone treatment (p<0.05). Conclusion In the present study risperidone caused a significant decrease in obsessive–compulsive symptoms in the treatment of schizophrenia. Copyright © 2003 John Wiley & Sons, Ltd.