Details

Autor(en) / Beteiligte

• Major, Louise L
• Edgar, Tina D
• Yee Yip, Po
• Isaksson, Leif A
• Tate, Warren P

Titel

Tandem termination signals: myth or reality?

Ist Teil von

• FEBS letters, 2002-03, Vol.514 (1), p.84-89

Ort / Verlag

England: Elsevier B.V

Erscheinungsjahr

2002

Link zum Volltext

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• In two Escherichia coli genomes, laboratory strain K-12 and pathological strain O157:H7, tandem termination codons as a group are slightly over-represented as termination signals. Individually however, they span the range of representations, over, as expected, or under, in one or both of the strains. In vivo, tandem termination codons do not make more efficient signals. The second codon can act as a backstop where readthrough of the first has occurred, but not at the expected efficiency. UGAUGA remains an enigma, highly over-represented, but with the second UGA a relatively inefficient back up stop codon.