Details

Autor(en) / Beteiligte

• Castro Hevia, J
• Dorticos Balea, F
• Dorantes Sánchez, M
• Zayas Molina, R
• Quiñones Pérez, M A

Titel

Unusual response to the ajmaline test in a patient with Brugada syndrome

Ist Teil von

• Europace (London, England), 2003-10, Vol.5 (4), p.371-373

Ort / Verlag

England

Erscheinungsjahr

2003

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• We present a Brugada syndrome patient who suffered an aborted sudden death. The ajmaline test (1 mg/kg body weight) induced accentuated alternans ST-segment elevation in V1-V2 without ventricular arrhythmias. It could represent silent ischaemia not detected before, failure of myocardial regions to repolarize in alternate beats due to transmural dispersion of conduction and refractoriness in the right ventricular outflow tract or a rate dependent sodium channel block by ajmaline. We need more studies to know whether this electrocardiographic sign is a risk factor for life-threatening ventricular arrhythmias in Brugada syndrome patients.