Details

Autor(en) / Beteiligte

• Wang, Jim X
• Knottnerus, Anne-Margreet
• Schuit, Giny
• Norman, Robert J
• Chan, Annabelle
• Dekker, Gus A

Titel

Surgically obtained sperm, and risk of gestational hypertension and pre-eclampsia

Ist Teil von

• The Lancet (British edition), 2002-02, Vol.359 (9307), p.673-674

Ort / Verlag

London: Elsevier Ltd

Erscheinungsjahr

2002

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• The cause of pre-eclampsia is unknown, although a partner-specific immune maladaptation might be involved. We compared rates of pre-eclampsia and gestational hypertension in women whose genital tracts had and had not been exposed to their partner's sperm cells. Our aim was to ascertain whether or not protective partner-specific immune-tolerance is conveyed by sperm cells, rather than seminal fluid. Our findings indicate that, compared with women exposed to their partner's sperm cells and seminal fluid—ie, those treated with in-vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) with ejaculated sperm—the risk of hypertension was doubled and the risk of pre-eclampsia tripled in those never exposed to their partner's sperm—ie, those treated with ICSI done with surgically obtained sperm.