Biological and Pharmaceutical Bulletin, 2002, Vol.25(2), pp.260-263
2002
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- Autor(en) / Beteiligte
- Titel
- Antipruritic Effect of Cnidii Monnieri Fructus (Fruits of Cnidium monnieri Cusson)
- Ist Teil von
- Biological and Pharmaceutical Bulletin, 2002, Vol.25(2), pp.260-263
- Ort / Verlag
- Tokyo: The Pharmaceutical Society of Japan
- Erscheinungsjahr
- 2002
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Antipruritic effects of 70% ethanol extract (CM-ext) of Cnidii Monnieri Fructus (dried fruits of Cnidium monnieri Cusson, Umberifferae) were investigated. In mice, an oral administration of CM-ext (200 and 500 mg/kg) inhibited compound 48/80-induced scratching behavior without influence on spontaneous locomotion. Isopimpinellin (3) and osthol (1), coumarin derivatives isolated from CM-ext, showed an inhibitory effect on compound 48/80-induced scratching behavior.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0918-6158eISSN: 1347-5215DOI: 10.1248/bpb.25.260Titel-ID: cdi_proquest_miscellaneous_71460128
- Format
- –
- Schlagworte
- Animals, antipruritic effect, Antipruritics - pharmacology, Biological and medical sciences, Cnidium monnieri, Coumarins - pharmacology, Fruit, General pharmacology, Histamine Release - drug effects, Ileum - drug effects, Ileum - physiology, isopimpinellin, Male, Medical sciences, Mice, Motor Activity - drug effects, osthol, p-Methoxy-N-methylphenethylamine - pharmacology, Pharmacognosy. Homeopathy. Health food, Pharmacology. Drug treatments, Phytotherapy, Plant Extracts - pharmacology, Rats, Rats, Wistar, Skin, nail, hair, dermoskeleton