The Journal of nutrition, 2003-12, Vol.133 (12), p.4267-4268
2003
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Nutrigenes, Functional Genomics and Systems Biology
- Ist Teil von
- The Journal of nutrition, 2003-12, Vol.133 (12), p.4267-4268
- Ort / Verlag
- Bethesda, MD: Elsevier Inc
- Erscheinungsjahr
- 2003
- Quelle
- Oxford Journals 2020 Medicine
- Beschreibungen/Notizen
- Traditionally, the classic reductionist approach attributes functions to individual genes. For instance, this has involved the analysis of motifs or the amino acid sequences of single gene products. It is unclear how the products of particular collections genes act together to provide higher order functionality in health and disease. To address this higher order problem, the function of collections of genes, as opposed to “one gene at a time” has to be studied. Accordingly, a model system is needed to test systems biology. In our studies, we used the homocysteine-folate metabolism as a model system.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0022-3166eISSN: 1541-6100DOI: 10.1093/jn/133.12.4267Titel-ID: cdi_proquest_miscellaneous_71431639
- Format
- –
- Schlagworte
- Animals, Biological and medical sciences, Biology - methods, Feeding. Feeding behavior, Folic Acid - metabolism, Fundamental and applied biological sciences. Psychology, Genes, Genomics - methods, Homocysteine - metabolism, homocysteine-folate metabolism, Mice, Models, Biological, neural-tube defects, Nutritional Physiological Phenomena - physiology, perturbations, systems biology, Vertebrates: anatomy and physiology, studies on body, several organs or systems