Carbohydrate research, 2003-10, Vol.338 (22), p.2265-2290
2003
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Details
- Autor(en) / Beteiligte
- Titel
- Synthesis of mono- and di-hydroxylated prolines and 2-hydroxymethylpyrrolidines from non-carbohydrate precursors
- Ist Teil von
- Carbohydrate research, 2003-10, Vol.338 (22), p.2265-2290
- Ort / Verlag
- Netherlands: Elsevier Ltd
- Erscheinungsjahr
- 2003
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Natural and synthetic imino sugars are biologically important as glycosidase inhibitors. This review includes selected syntheses of 3-hydroxyproline, 4-hydroxyproline, 3,4-dihydroxyproline, 2-hydroxymethyl-3-hydroxypyrrolidine and 2-hydroxymethyl-pyrrolidine-3,4-diol, which exhibit glycosidase inhibitory and various other biological activities. Graphic
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0008-6215eISSN: 1873-426XDOI: 10.1016/j.carres.2003.09.002Titel-ID: cdi_proquest_miscellaneous_71291505
- Format
- –
- Schlagworte
- Animals, Arabinose, Carbohydrates - chemistry, Deoxy imino sugars, Dihydroxyproline, Glycosidase inhibitors, Glycoside Hydrolases - antagonists & inhibitors, Glycoside Hydrolases - metabolism, Hydroxyproline, Hydroxyproline - analogs & derivatives, Hydroxyproline - chemical synthesis, Hydroxyproline - chemistry, Hydroxyproline - isolation & purification, Hydroxypyrrolidine, Imino Furanoses, Stereoisomerism, Sugar Alcohols - chemical synthesis, Sugar Alcohols - chemistry