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A review of antimycobacterial natural products
Phytotherapy research, 2000-08, Vol.14 (5), p.303-322
Newton, Sandra M.
Lau, Clara
Wright, Colin W.
2000
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Newton, Sandra M.
Lau, Clara
Wright, Colin W.
Titel
A review of antimycobacterial natural products
Ist Teil von
Phytotherapy research, 2000-08, Vol.14 (5), p.303-322
Ort / Verlag
Chichester, UK: John Wiley & Sons, Ltd
Erscheinungsjahr
2000
Quelle
MEDLINE
Beschreibungen/Notizen
Tuberculosis is a chronic infectious disease caused by several species of mycobacteria. Due to multi‐drug resistant strains of mycobacteria and to a high prevalence of tuberculosis in patients who have acquired human immunodeficiency syndrome (AIDS), the number of patients infected with the disease is increasing worldwide. Thus there is an urgent need for new effective antimycobacterial agents to replace those currently in use. In this instance, the plant kingdom is undoubtedly a valuable source for new anti‐tuberculosis agents. The present review article reports the findings from an extensive literature search of all plants that have been assessed for antimycobacterial/antitubercular activity over the past 20–30 years. An attempt has been made to summarize the information in order to highlight those promising plant species which are worthy of further investigation as leads for drug development. Over 350 plant species from a wide range of families and origins, containing various chemical classes of compounds, have been screened for such activity. A review of the relevant in vitro assays using different species of pathogenic and non‐pathogenic mycobacteria is also included. Copyright © 2000 John Wiley & Sons, Ltd.
Sprache
Englisch
Identifikatoren
ISSN: 0951-418X
eISSN: 1099-1573
DOI: 10.1002/1099-1573(200008)14:5<303::AID-PTR712>3.0.CO;2-N
Titel-ID: cdi_proquest_miscellaneous_71270542
Format
–
Schlagworte
antimycobacterial
,
Antitubercular Agents - therapeutic use
,
Biological and medical sciences
,
Formularies as Topic
,
General pharmacology
,
Humans
,
Medical sciences
,
mycobacteria
,
Mycobacterium tuberculosis - drug effects
,
natural products
,
Pharmacognosy. Homeopathy. Health food
,
Pharmacology. Drug treatments
,
Phytotherapy
,
plants
,
Plants, Medicinal - therapeutic use
,
traditional medicine
,
tuberculosis
,
Tuberculosis - drug therapy
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