Details

Autor(en) / Beteiligte

• Chen, Yueh-Sheng
• Hu, Cheng-Li
• Hsieh, Ching-Liang
• Lin, Jaung-Geng
• Tsai, Chin-Chuan
• Chen, Ter-Hsin
• Yao, Chun-Hsu

Titel

Effects of percutaneous electrical stimulation on peripheral nerve regeneration using silicone rubber chambers

Ist Teil von

• Journal of biomedical materials research, 2001-12, Vol.57 (4), p.541-549

Ort / Verlag

New York: John Wiley & Sons, Inc

Erscheinungsjahr

2001

Link zum Volltext

Quelle

Wiley(RISS)

Beschreibungen/Notizen

• The purpose of this study was to determine whether 0.8–1 mA, 2 Hz of percutaneous electrical stimulation could affect the regeneration of a 10‐mm gap of rat sciatic nerve created between the proximal and distal nerve stumps, which were sutured into silicone rubber tubes. Six weeks after implantation, though the group receiving the electrical stimulation had a lower success percentage of regeneration (57%) compared with the controls receiving no stimulation (70%), quantitative histology of the successfully regenerated nerves revealed that the mean values of the axon density, blood vessel number, blood vessel area, and percentage of blood vessel area in total nerve area in the group with the electrical stimulation were all significantly larger than those in the controls (p < 0.05). These results showed that the electrical stimulation could elicit rehabilitating effects on the regenerated nerves. © 2001 John Wiley & Sons, Inc. J Biomed Mater Res 57: 541–549, 2001