Details

Autor(en) / Beteiligte

• Slonim, Alfred E
• Bulone, Linda
• Damore, Mary B
• Goldberg, Teresia
• Wingertzahn, Mark A
• McKinley, Matthew J

Titel

A Preliminary Study of Growth Hormone Therapy for Crohn's Disease

Ist Teil von

• The New England journal of medicine, 2000-06, Vol.342 (22), p.1633-1637

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2000

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Crohn's disease is a debilitating multisystem disorder whose cause is uncertain. It is characterized by inflammation of the bowel, which usually begins during adolescence or early adulthood and often leads to catabolism. 1 To reduce the inflammation and induce remission, patients with Crohn's disease are treated with immunosuppressive and antiinflammatory drugs that often have severe side effects and that, in some cases, enhance the catabolic process. Attempts to counteract the effects of the disease through the use of high-protein diets have been partially successful. 2 The effect of regulatory peptides such as growth hormone 3 and insulin-like growth factor I 4 on intestinal growth . . .