Details

Autor(en) / Beteiligte

• Shen, Yue-quan
• Tang, Liang
• Zhou, Hai-meng
• Lin, Zheng-jiong

Titel

Structure of human muscle creatine kinase

Ist Teil von

• Acta crystallographica. Section D, Biological crystallography., 2001-08, Vol.57 (8), p.1196-1200

Ort / Verlag

5 Abbey Square, Chester, Cheshire CH1 2HU, England: Munksgaard International Publishers

Erscheinungsjahr

2001

Quelle

MEDLINE

Beschreibungen/Notizen

• The crystal structure of human muscle creatine kinase has been determined by the molecular‐replacement method and refined at 3.5 Å resolution. The structures of both the monomer and the dimer closely resemble those of the other known structures in the creatine kinase family. Two types of dimers, one with a non‐crystallographic twofold symmetry axis and the other with a crystallographic twofold symmetry axis, were found to occur simultaneously in the crystal. These dimers form an infinite `double‐helix'‐like structure along an unusual long crystallographic 31 axis.