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Improved technique for infrahepatic vena cava reconstruction in guinea pig-to-rat liver transplantation
Microsurgery, 2000, Vol.20 (3), p.139-142
Mark, Walter
Candinas, Daniel
Hechenleitner, Paul
Hengster, Paul
Obrist, Peter
Klima, Günther
Margreiter, Raimund
2000
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Mark, Walter
Candinas, Daniel
Hechenleitner, Paul
Hengster, Paul
Obrist, Peter
Klima, Günther
Margreiter, Raimund
Titel
Improved technique for infrahepatic vena cava reconstruction in guinea pig-to-rat liver transplantation
Ist Teil von
Microsurgery, 2000, Vol.20 (3), p.139-142
Ort / Verlag
New York: John Wiley & Sons, Inc
Erscheinungsjahr
2000
Quelle
Wiley Blackwell Single Titles
Beschreibungen/Notizen
Guinea pig–to–rat orthotopic liver transplantation is associated with serious technical problems contributing to impaired graft perfusion and primary graft failure. In order to shorten the procurement procedure and thereby minimize liver damage before flushing, a simplified technique for infrahepatic caval reconstruction was developed. Dissection of the infrahepatic vena cava (IHVC) from adrenal glands and renal and lumbar veins represents the most difficult and time‐consuming part of the donor operation, which is often not well tolerated by the animal; we avoided this step by using an isogeneic vena cava interposition graft (VCIG) following in situ perfusion. This graft is connected with the IHVC transsected just below the liver with a cuff technique. Donor operations lasted 15 to 20 minutes with the new technique (n = 7) compared to 52 to 76 minutes with conventional technique (n = 7). Reduced operating time was associated with markedly improved graft perfusion and significantly better graft survival. This modification of the donor procedure for the guinea pig–to–rat liver xenograft using a VCIG significantly reduces operating time and improves reperfusion and recipient survival. © 2000 Wiley‐Liss, Inc. MICROSURGERY 20:139–142 2000
Sprache
Englisch
Identifikatoren
ISSN: 0738-1085
eISSN: 1098-2752
DOI: 10.1002/(SICI)1098-2752(2000)20:3<139::AID-MICR8>3.0.CO;2-9
Titel-ID: cdi_proquest_miscellaneous_71075702
Format
–
Schlagworte
Anastomosis, Surgical
,
Animals
,
Biological and medical sciences
,
Blood Vessel Prosthesis Implantation
,
Female
,
Guinea Pigs
,
Liver Transplantation
,
Liver, biliary tract, pancreas, portal circulation, spleen
,
Medical sciences
,
Microsurgery
,
Rats
,
Rats, Inbred Lew
,
Reconstructive Surgical Procedures
,
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
,
Surgery of the digestive system
,
Transplantation, Heterologous
,
Vena Cava, Inferior - surgery
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