Details

Autor(en) / Beteiligte

• Nickeleit, Volker
• Klimkait, Thomas
• Binet, Isabelle F
• Dalquen, Peter
• Del Zenero, Veronika
• Thiel, Gilbert
• Mihatsch, Michael J
• Hirsch, Hans H

Titel

Testing for Polyomavirus Type BK DNA in Plasma to Identify Renal-Allograft Recipients with Viral Nephropathy

Ist Teil von

• The New England journal of medicine, 2000-05, Vol.342 (18), p.1309-1315

Ort / Verlag

Boston, MA: Massachusetts Medical Society

Erscheinungsjahr

2000

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• The human polyomaviruses BK virus and JC virus are nonenveloped viruses that have a diameter of 45 nm and a circular, double-stranded–DNA genome of 5300 bp. 1 Each of the two viruses is 70 percent homologous with the other and with simian virus 40 (SV40). 1 Typically, primary infection with the BK virus or JC virus occurs during childhood and does not produce specific symptoms; the prevalence on serologic testing is more than 80 percent among adults worldwide. 1 , 2 Serologic studies suggest that the BK virus and JC virus are transmitted independently of one another, most likely by the oral or respiratory . . .