Details

Autor(en) / Beteiligte

• Shi, K H
• Lim, S S
• Jung, S H
• Ji, J
• Lee, E B
• Kim, D C
• Shin, K J
• Kim, D J
• Park, S W

Titel

Synthesis and anti-inflammatory and analgesic activities of pyridyloxy- and phenoxyalkanoic acid derivatives

Ist Teil von

• Archives of pharmacal research, 2000-02, Vol.23 (1), p.17-21

Ort / Verlag

Korea (South)

Erscheinungsjahr

2000

Quelle

springer (창간호~2014)

Beschreibungen/Notizen

• Synthesis of pyridyloxy-, pyridyloxyphenoxy- and phenoxylphenoxyalkanate derivatives and their anti-inflammatory and analgesic activities were investigated. Analysis of structure-activity relationships showed that in pyridyloxyalkanoic acid derivatives anti-edematous potency was associated with the presence of chlorophenoxypropionic acid moiety and 2-nitrated methyl propionates contributed to the analgesic activity.